Altered esophageal motility during perception of bolus transit in healthy volunteers

Costa TV, Dantas RO. Background – The perception of bolus transit through the thoracic esophagus may be caused by altered esophageal anatomy and function. Objective – To evaluate the hypothesis that, in healthy volunteers, swallows followed by perception of esophageal bolus transit are associated with changes in esophageal motility. Methods – Simultaneous evaluation of motility…

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Lymphocyte count and platelet volume predicts postoperative complications in esophagectomy for cancer: a cohort study

Tustumi F, Takeda FR, Brandão AAGS, Sallum RAA, Ribeiro Junior U, Cecconello I. Background – Biomarkers from routine complete blood count are known predictive factors of long-term outcomes in cancer patients. The value of these biomarkers in the setting of trimodal therapy for esophageal cancer in predicting early postoperative outcomes is not studied. Objective –…

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Mental disorders and quality of life in patients awaiting liver transplantation

Guerreiro-Costa LNF, Araujo-Filho JEO, Marback RF, Jesus-Nunes AP, Morais-de-Jesus M, Quarantini LC. Background – Liver transplantation is the main therapeutic alternative for patients with advanced liver disease. These patients have high prevalence of psychiatric comorbidities that may negatively interfere in clinical outcomes and quality of life. It is not clear in the literature whether the…

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Biological therapy penetration for inflammatory bowel disease in Latin America: current status and future challenges

Background – The introduction of anti-TNF agents represented a landmark in the management of both Crohn’s disease (CD) and ulcer­ative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facilitate the access of biological agents for physicians and patients. Objective – The aim…

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