Altered esophageal motility during perception of bolus transit in healthy volunteers

Costa TV, Dantas RO. Background – The perception of bolus transit through the thoracic esophagus may be caused by altered esophageal anatomy and function. Objective – To evaluate the hypothesis that, in healthy volunteers, swallows followed by perception of esophageal bolus transit are associated with changes in esophageal motility. Methods – Simultaneous evaluation of motility…

Lymphocyte count and platelet volume predicts postoperative complications in esophagectomy for cancer: a cohort study

Tustumi F, Takeda FR, Brandão AAGS, Sallum RAA, Ribeiro Junior U, Cecconello I. Background – Biomarkers from routine complete blood count are known predictive factors of long-term outcomes in cancer patients. The value of these biomarkers in the setting of trimodal therapy for esophageal cancer in predicting early postoperative outcomes is not studied. Objective –…

Mental disorders and quality of life in patients awaiting liver transplantation

Guerreiro-Costa LNF, Araujo-Filho JEO, Marback RF, Jesus-Nunes AP, Morais-de-Jesus M, Quarantini LC. Background – Liver transplantation is the main therapeutic alternative for patients with advanced liver disease. These patients have high prevalence of psychiatric comorbidities that may negatively interfere in clinical outcomes and quality of life. It is not clear in the literature whether the…

Biological therapy penetration for inflammatory bowel disease in Latin America: current status and future challenges

Background – The introduction of anti-TNF agents represented a landmark in the management of both Crohn’s disease (CD) and ulcer­ative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facilitate the access of biological agents for physicians and patients. Objective – The aim…

Increased risk of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors

Background – Endoscopic mucosal resection is one of the most frequent therapeutic alternatives for large colorectal lateral spreading tumors. There are few data on the prevalence of synchronous lesions on these patients. Objective – To describe the prevalence of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors >20 mm.m.br/wp-admin/post-new.php?classic-editor&post_type=post&source_lang=pt-br&trid=2894&lang=en&admin_bar=1…

Evaluation of psoriasis treatment with esomeprazole – a pilot study

Background – Psoriasis is an inflammatory skin disease that affects 1%–3% of Caucasian populations and may be persistent, disfiguring and stigmatizing. Proton pump inhibitors (PPI) are potent blockers of gastric acid secretion. They are widely regarded as the agents of choice for the treatment of acid-peptic disorders. In addition to anti-secretory effects PPI have been…

Bariatric surgery and binge eating disorder: should surgeons care about it? A literature review of prevalence and assessment tools

Tess BH, Maximiano-Ferreira L, Pajecki D, Wang YP. ABSTRACT Background – Eating pathologies among bariatric surgery candidates are common and associated with adverse surgical outcomes, including weight regain and low quality of life. However, their assessment is made difficult by the great variety and inconsistent use of standardized measures. Objective – The purpose of this…

Safety and efficacy of EUS-guided coil plus cyanoacrylate versus conventional cyanoacrylate technique in the treatment of gastric varices: a randomized controlled trial

Lôbo MRA, Chaves DM, de Moura DTH, Ribeiro IB, Ikari E, de Moura EGH. ABSTRACT Background – One of the most feared complications with the use of cyanoacrylate for treatment of gastric varices is the occurrence of potentially life-threatening systemic embolism. Thus, endoscopists are turning towards new techniques, including endoscopic coiling, as a potentially safer…

Chronic hepatitis C is still a problem for the public health care system in Brazil

Edna Strauss. Arq Gastroenterol. 2018;55(4):321-3. Globally, about 80 million people are living with the hepatitis C virus (HCV). In 2016, the World Health Organization (WHO) adopted the Global Health Sector Strategy on Viral Hepatitis to eliminate hepatitis by 2030. This commitment was proposed in response to the growing prevalence of chronic viral hepatitis worldwide. The…

Irritable bowel syndrome, food intolerance and non- celiac gluten sensitivity. A new clinical challenge

Rosa Leonôra Salerno SOARES. Arq Gastroenterol. 2018;55(4):417-22. ABSTRACT – Approximately 80% of irritable bowel syndrome (IBS) patients report that their symptoms are triggered after ingesting one or specific food groups. Gluten, wheat and related proteins (e.g., amylase-trypsin inhibitors, and fermentable oligo-di-mono-saccharides and polyols (FODMAPs)are the most relevant IBS symptom triggers, although the true ‘culprit(s)’ is/are…