Biological therapy penetration for inflammatory bowel disease in Latin America: current status and future challenges

Background – The introduction of anti-TNF agents represented a landmark in the management of both Crohn’s disease (CD) and ulcer­ative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facilitate the access of biological agents for physicians and patients. Objective – The aim…

Increased risk of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors

Background – Endoscopic mucosal resection is one of the most frequent therapeutic alternatives for large colorectal lateral spreading tumors. There are few data on the prevalence of synchronous lesions on these patients. Objective – To describe the prevalence of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors >20 mm.m.br/wp-admin/post-new.php?classic-editor&post_type=post&source_lang=pt-br&trid=2894&lang=en&admin_bar=1…

Evaluation of psoriasis treatment with esomeprazole – a pilot study

Background – Psoriasis is an inflammatory skin disease that affects 1%–3% of Caucasian populations and may be persistent, disfiguring and stigmatizing. Proton pump inhibitors (PPI) are potent blockers of gastric acid secretion. They are widely regarded as the agents of choice for the treatment of acid-peptic disorders. In addition to anti-secretory effects PPI have been…

Bariatric surgery and binge eating disorder: should surgeons care about it? A literature review of prevalence and assessment tools

Tess BH, Maximiano-Ferreira L, Pajecki D, Wang YP. ABSTRACT Background – Eating pathologies among bariatric surgery candidates are common and associated with adverse surgical outcomes, including weight regain and low quality of life. However, their assessment is made difficult by the great variety and inconsistent use of standardized measures. Objective – The purpose of this…

Safety and efficacy of EUS-guided coil plus cyanoacrylate versus conventional cyanoacrylate technique in the treatment of gastric varices: a randomized controlled trial

Lôbo MRA, Chaves DM, de Moura DTH, Ribeiro IB, Ikari E, de Moura EGH. ABSTRACT Background – One of the most feared complications with the use of cyanoacrylate for treatment of gastric varices is the occurrence of potentially life-threatening systemic embolism. Thus, endoscopists are turning towards new techniques, including endoscopic coiling, as a potentially safer…

Chronic hepatitis C is still a problem for the public health care system in Brazil

Edna Strauss. Arq Gastroenterol. 2018;55(4):321-3. Globally, about 80 million people are living with the hepatitis C virus (HCV). In 2016, the World Health Organization (WHO) adopted the Global Health Sector Strategy on Viral Hepatitis to eliminate hepatitis by 2030. This commitment was proposed in response to the growing prevalence of chronic viral hepatitis worldwide. The…

Irritable bowel syndrome, food intolerance and non- celiac gluten sensitivity. A new clinical challenge

Rosa Leonôra Salerno SOARES. Arq Gastroenterol. 2018;55(4):417-22. ABSTRACT – Approximately 80% of irritable bowel syndrome (IBS) patients report that their symptoms are triggered after ingesting one or specific food groups. Gluten, wheat and related proteins (e.g., amylase-trypsin inhibitors, and fermentable oligo-di-mono-saccharides and polyols (FODMAPs)are the most relevant IBS symptom triggers, although the true ‘culprit(s)’ is/are…

The old one technique in a new style: developing procedural skills in paracentesis in a low cost simulator model

Mesquita DAK, Queiroz EF, Oliveira MA, Cunha CMQ, Maia FM, Correa RV. Arq Gastroenterol. 2018;55(4):375-9. ABSTRACT – Background – Paracentesis is a routine medical procedure quite relevant in clinical practice. There are risks of complications related to paracentesis, so it is essential a proper trainee for the younger practicer. Objective – The article describes the…

NEURAL CONTROL OF SWALLOWING

BACKGROUND Swallowing is a motor process with several discordances and a very difficult neurophysiological study. Maybe that is the reason for the scarcity of papers about it. OBJECTIVE It is to describe the chewing neural control and oral bolus qualification. A review the cranial nerves involved with swallowing and their relationship with the brainstem, cerebellum,…

CAN THREE-DIMENSIONAL ANORECTAL ULTRASONOGRAPHY BE INCLUDED AS A DIAGNOSTIC TOOL FOR THE ASSESSMENT OF ANAL FISTULA ?

BACKGROUND: There is no a clear knowledge concerning the division of any part of the anal sphincter complex and the effect of this procedure on the function of the anal canal during the treatment of perianal fistula. OBJECTIVE: To evaluate the usefulness of 3D anorectal ultrasound in the assessment of anal fistula, quantifying the length…