Normal values of esophageal high-resolution manometry: a Brazilian multicenter study

Gerson Ricardo DOMINGUES, Nelson Henrique MICHELSOHN, Ricardo Guilherme VIEBIG, Décio CHINZON, Ary NASI, Carla Granja ANDRADE, Eponina Maria LEMME, Luiz João ABRAHÃO JUNIOR, Mauricio Gustavo BRAVIM, Miguel Ângelo NOBRE-E-SOUZA, Nayara Salgado CARVALHO, Paulo J P C CARVALHO, Tomás Navarro RODRIGUES, Joaquim Prado P MORAES FILHO Background – The high-resolution manometry has been a significant advance…

Underwater endoscopic mucosal resection for non-pedunculated colorectal lesions. A prospective single-arm study

Luciano LENZ, Bruno MARTINS, Fabio Shiguehisa KAWAGUTI, Alexandre TELLIAN, Caterina Maria Pia Simoni PENNACHI, Mauricio SORBELLO, Carla GUSMON, Gustavo Andrade de PAULO, Ricardo UEMURA, Sebastian GEIGER, Marcelo Simas de LIMA, Adriana SAFATLE-RIBEIRO, Elisa BABA, Claudio Lyoiti HASHIMOTO, Fauze MALUF-FILHO, Ulysses RIBEIRO JR Background – Underwater endoscopic mucosal resection (UEMR) has emerged as a revolutionary method…

Patterns of fiber intake among Brazilian adults: perceptions from an online nationwide survey

Maria do Carmo F PASSOS, Maira Libertad Soligo TAKEMOTO, Luciana S GUEDES Background – Adequate fiber intake is associated with digestive health and reduced risk of several noncommunicable diseases and is recognized as essential for human health (World Health Organization, 2003). The World Health Organization (WHO) recommends a daily fiber consumption of ≥25 g, but…

Hepatocellular carcinoma patients are advantaged in the current Brazilian liver transplant allocation system. A competing risk analysis

Santiago RODRÍGUEZ, Alfeu de Medeiros FLECK JR, Marcos MUCENIC, Cláudio MARRONI, Ajacio BRANDÃO Background – In Brazil, the Model for End-Stage Liver Disease (MELD) score is used to prioritize patients for deceased donor liver transplantation (DDLT). Patients with hepatocellular carcinoma (HCC) receive standardized MELD exception points to account for their cancer risk of mortality, which…

Peroral (POEM) or surgical myotomy for the treatment of achalasia: a systematic review and meta-analysis

Rafael Krieger MARTINS, Igor Braga RIBEIRO, Diogo Turiani Hourneaux DE MOURA, Kelly E HATHORN, Wanderley Marques BERNARDO, Eduardo Guimarães Hourneaux DE MOURA Background – Achalasia is a neurodegenerative motility esophageal disorder characterized by failure of lower esophageal sphincter relaxation. The conventional treatment option for achalasia has been laparoscopic Heller myotomy (LHM). However, in 2010, Inoue…

Altered esophageal motility during perception of bolus transit in healthy volunteers

Costa TV, Dantas RO. Background – The perception of bolus transit through the thoracic esophagus may be caused by altered esophageal anatomy and function. Objective – To evaluate the hypothesis that, in healthy volunteers, swallows followed by perception of esophageal bolus transit are associated with changes in esophageal motility. Methods – Simultaneous evaluation of motility…

Lymphocyte count and platelet volume predicts postoperative complications in esophagectomy for cancer: a cohort study

Tustumi F, Takeda FR, Brandão AAGS, Sallum RAA, Ribeiro Junior U, Cecconello I. Background – Biomarkers from routine complete blood count are known predictive factors of long-term outcomes in cancer patients. The value of these biomarkers in the setting of trimodal therapy for esophageal cancer in predicting early postoperative outcomes is not studied. Objective –…

Mental disorders and quality of life in patients awaiting liver transplantation

Guerreiro-Costa LNF, Araujo-Filho JEO, Marback RF, Jesus-Nunes AP, Morais-de-Jesus M, Quarantini LC. Background – Liver transplantation is the main therapeutic alternative for patients with advanced liver disease. These patients have high prevalence of psychiatric comorbidities that may negatively interfere in clinical outcomes and quality of life. It is not clear in the literature whether the…

Biological therapy penetration for inflammatory bowel disease in Latin America: current status and future challenges

Background – The introduction of anti-TNF agents represented a landmark in the management of both Crohn’s disease (CD) and ulcer­ative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facilitate the access of biological agents for physicians and patients. Objective – The aim…