Biological therapy penetration for inflammatory bowel disease in Latin America: current status and future challenges

Background – The introduction of anti-TNF agents represented a landmark in the management of both Crohn’s disease (CD) and ulcer­ative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facilitate the access of biological agents for physicians and patients. Objective – The aim…

Increased risk of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors

Background – Endoscopic mucosal resection is one of the most frequent therapeutic alternatives for large colorectal lateral spreading tumors. There are few data on the prevalence of synchronous lesions on these patients. Objective – To describe the prevalence of synchronous colorectal lesions in patients referred for endoscopic mucosal resection of lateral spreading tumors >20 mm.m.br/wp-admin/post-new.php?classic-editor&post_type=post&source_lang=pt-br&trid=2894&lang=en&admin_bar=1…

Evaluation of psoriasis treatment with esomeprazole – a pilot study

Background – Psoriasis is an inflammatory skin disease that affects 1%–3% of Caucasian populations and may be persistent, disfiguring and stigmatizing. Proton pump inhibitors (PPI) are potent blockers of gastric acid secretion. They are widely regarded as the agents of choice for the treatment of acid-peptic disorders. In addition to anti-secretory effects PPI have been…