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Categoria: Hepatologia

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Validation of the PAGE-B score as a prognosis of development to hepatocellular carcinoma (HCC) in chronic hepatitis B, in the Brazilian population

Validation of the PAGE-B score as a prognosis of development to hepatocellular carcinoma (HCC) in chronic hepatitis B, in the Brazilian population

This study provides robust real-world evidence validating the PAGE-B score as an effective and practical tool for predicting hepatocellular carcinoma risk among Brazilian patients with chronic hepatitis B receiving long-term antiviral therapy. The higher incidence of HCC observed, particularly among older male patients with thrombocytopenia and advanced fibrosis, underscores the need for region-specific risk stratification strategies. By confirming the discriminatory capacity of PAGE-B in a diverse Brazilian population and highlighting differences related to antiviral therapy, these findings support its incorporation into routine clinical practice to optimize surveillance intensity and improve early HCC detection in high-risk HBV carriers.

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Incidental hepatic steatosis identified on ultrasound in patients undergoing cholecystectomy: high prevalence and insufficient investigative and clinical management

Incidental hepatic steatosis identified on ultrasound in patients undergoing cholecystectomy: high prevalence and insufficient investigative and clinical management

This study evaluated the prevalence and management of incidental hepatic steatosis found on ultrasounds of patients who underwent elective cholecystectomy. The study highlighted that steatosis has not received proper medical attention, with little documentation, research or advice on lifestyle changes.