HIGHLIGHTS
- Descriptive, cross-sectional study in a Colombian IBD Centre of Excellence (adults and paediatrics, inpatients and outpatients).
- To assess the association between nutritional status and quality of life in patients with inflammatory bowel disease (IBD).
- MUST and MIRT (adults); STRONG Kids (paediatrics); EQ-5D and IBDQ-32 for quality of life.
- Malnutrition was present in >60% of hospitalized patients; strongly associated with poor quality of life. Nutritional support improved outcomes.
- Study conducted by a team of gastroenterologists, nutritionists, paediatricians, and clinical researchers.
- First study in Colombia evaluating nutritional status and QoL in IBD patients using structured screening and follow-up.
- Recommends routine nutritional screening and support as essential components of IBD management.
ABSTRACT
Background –
Inflammatory bowel disease (IBD) significantly affects patients’ nutritional status and quality of life (QoL). Nutritional deficiencies are frequent and may worsen disease outcomes. The aim of this study is to assess the association between nutritional status and quality of life in patients with IBD. Methods – A cross-sectional study was conducted in a specialised IBD centre. Nutritional status was evaluated using the MUST and MIRT tools in adults and the “Strong Kids” scale in paediatrics. An individualised nutritional support protocol was implemented. Quality of life was assessed with the EQ-5D and IBDQ-32 instruments. Results – Among 90 patients, 26.6% required hospitalisation, predominantly adults and females. The mean age was 36.7 years. Crohn’s disease (CD) was more prevalent (58.3%), and 83.3% received biological therapy. Malnutrition risk in hospitalised patients with ulcerative colitis (UC) and CD was significantly increased, with odds ratios of 8.33 (95%CI: 1.16-27) and 25 (95%CI: 11.6-45.2), respectively. All hospitalised patients with severe disease presented with malnutrition. In the paediatric group, 87.5% received enteral nutrition and 25% required parenteral nutrition. Nutritional support improved nutritional status in 75% of cases within three months. Malnutrition was significantly associated with poorer QoL, particularly affecting mobility, self-care, and daily activities (P<0.05). Conclusion – Malnutrition has a substantial negative impact on quality of life in IBD patients. Early detection using tools such as MUST, MIRT, and strong kids is essential. Integrating systematic nutritional screening and tailored support into routine clinical practice is imperative to improve outcomes and promote recovery.
AUTORES
Viviana PARRA-IZQUIERDO, Carlos Augusto CUADROS, Ginary ORDUZ-DIAZ, Paula Daniela BONILLA-RIBERO, Oscar Mariano PINTO, Cristian Fabian FLOREZ, Juan Javier ACEVEDO, Julian FERREIRA, Vanessa DURAN, Luis Felipe MURCIA and Juan Sebastian FRIAS-ORDOÑEZ
